Federated Learning-Based Privacy-Preserving Intelligence for Secure Healthcare and Distributed Enterprise Applications
DOI:
https://doi.org/10.15680/IJMRSETM.2026.0210001Keywords:
Federated Learning, Privacy-Preserving Intelligence, Secure Healthcare, Distributed Enterprise Applications, Differential Privacy, Secure Aggregation, Distributed Machine LearningAbstract
Federated learning has emerged as a promising approach for developing privacy-preserving intelligent systems across healthcare and distributed enterprise environments where sensitive data cannot be freely centralized. Conventional machine learning architectures require organizations to transfer data to centralized repositories, creating risks related to privacy breaches, regulatory non-compliance, communication overhead, and unauthorized data exposure. This research proposes a federated learning-based privacy-preserving intelligence framework that enables multiple healthcare institutions and enterprise organizations to collaboratively develop machine learning models while retaining sensitive information within local infrastructures. The framework integrates distributed model training, secure aggregation, privacy-aware communication, adaptive client selection, model validation, and governance mechanisms. Healthcare and enterprise participants independently preprocess local datasets and train machine learning models before securely transmitting model updates to an aggregation layer. The aggregated global model is subsequently distributed to participating clients for iterative improvement without directly exchanging raw records. The methodology evaluates predictive performance, privacy protection, communication efficiency, computational overhead, scalability, and robustness under heterogeneous data distributions. The proposed framework is designed to support applications including clinical prediction, patient risk assessment, fraud detection, cybersecurity analytics, operational forecasting, and intelligent enterprise decision-making. By combining decentralized learning with privacy-enhancing mechanisms and distributed governance, the framework provides a foundation for secure collaborative intelligence. The research emphasizes trustworthy model development while maintaining organizational data sovereignty, interoperability, and scalable intelligent analytics across heterogeneous environments.
References
1. Neela, S. (2022). Toward intelligent enterprise integration: Cloud-native middleware design patterns and adaptive stream orchestration architectures for autonomous real-time decisioning. International Journal of Artificial Intelligence, Data Science, and Machine Learning, 3(2), 154–164.
2. Nabil, M. A., Akand, A. R., Datta, A., Akter, K. S., Hossain, I., & Prince, N. U. (2026, August). A Multi-Dimensional Supervised Machine Learning Framework for Cybersecurity-Focused Social Media Bot Detection. In 2026 7th International Conference On Computational Vision and Bio Inspired Computing (ICCVBIC) (pp. 88-93). IEEE.
3. Mathew, A. (2021). Artificial intelligence and cognitive computing for 6G communications & networks. International Journal of Computer Science and Mobile Computing, 10(3), 26-31.
4. Kalakoti, M. K. R. (2025). Provider-agnostic infrastructure as code: A modular framework for secure multi-tenant cloud automation. Journal of international crisis and risk communication research, 188-197.
5. Kasarapu, B. C. (2026). An Intelligent Frontend Architecture for Retail Systems Using Transformer Models and Reinforcement Learning for Adaptive User Interfaces. American Academic Journal, 178-185.
6. Chundi, V. R. K., Agarwal, V., & Arya, P. (2025, November). Green AI for Sustainable Supply Chains: Challenges in Emerging Economies. In 2025 International Conference on Computational Engineering, Sensing Technology and Management (ICCETM) (pp. 1-5). IEEE.
7. Yadavalli, V. R. (2023). Cutover intelligence mesh: A dependency-aware architecture for enterprise cloud ERP migration. International Journal of Future Innovative Science and Technology, 6(4), 11015–11031.
8. Selvarajan, K. (2026). AI-powered security health analytics: A scalable framework for enterprise risk and operational intelligence. International Journal of Humanities and Information Technology, 8(3), 33–41.
9. Venkatasalam, K., Rajendran, P., & Thangavel, M. (2019). Improving the accuracy of feature selection in big data mining using accelerated flower pollination (AFP) algorithm. Journal of medical systems, 43(4), 96.
10. Chinnam, N. B. (2026). Agentic AI for autonomous enterprise quality-gate onboarding and software delivery. International Journal of Research and Applied Innovations, 9(1), 13729–13733.
11. Kagga, S. R., Ayyagari, V., & Rekulapalli, K. (2026, June). Federated Learning for Dialysis Outcome Prediction Across Hospitals. In 2026 5th International Conference on Computer Networks, Big Data and IoT (ICCBI) (pp. 533-538). IEEE.
12. Pothuri, M. K. (2025). How modern BI stacks power smarter, faster decision-making in public health care—Blueprint of a modern BI architecture: Designing for scale, speed, and self-service. International Journal for Multidisciplinary Research, 7(5). https://doi.org/10.36948/ijfmr.2025.v07i05.57947
13. Nelavala, M. M. (2026). Protocol-Aware Chaos Engineering for SWIFT Gpi-Compatible Microservices: A Framework for Five-Nines Cross-Border Payment Resilience. Journal of Intelligent Decision Making and Information Science, 3(10s), 621-637.
14. Ramasamy, M. (2025). Transforming industries: The impact of AI-driven network engineering and cloud infrastructure. International Journal of Research and Applied Innovations, 8(3), 13114–13118.
15. Aragani, V. M., Maroju, P. K., & Mudunuri, L. N. R. (2024, December). Implementing Non-functional Production Regression Testing with Kubernetes. In International Conference on Information and Communication Technology for Competitive Strategies (pp. 231-244). Singapore: Springer Nature Singapore.
16. Hossain, M. S., & Rahaman, M. M. (2026). A Comprehensive Cyber Security Architecture for Government Agencies based on the AITIR Framework. Journal of Intelligent Decision Making and Information Science, 3(9s), 1248-1266.
17. Sugumar, R. (2021). Generative AI Pipelines for Safety Validation of Autonomous Driving Models. International Journal of Advanced Research in Computer Science & Technology (IJARCST), 4(5), 5466-5469.
18. Bandari, U., & Perumal, R. S. (2025). Copilots for self-service BI: A practitioner comparison of generative analytics assistants across enterprise data platforms. International Journal of Engineering & Extended Technologies Research, 7(6), 11312–11322.
19. Tatavarthi, S., Bikkavolu, V., Gulapalli, S., Koilakonda, R. R., & Divi, V. R. (2026, July). HybridFraudNet: A Dual-Branch CNN-GNN Architecture for Healthcare Insurance Fraud Detection. In 2026 Seventeenth International Conference on Ubiquitous and Future Networks (ICUFN) (pp. 917-922). IEEE.
20. Yasin, M., Akter, S., Khan, M. A. N., Tasnim, M., Sultana, S., Jakir, T., ... & Akter, K. S. (2026). XAI-Enabled Intelligent Detection and Mitigation of Zero-Day Attacks in Healthcare IoT. International Journal of Future Innovative Science and Technology (IJFIST), 9(5), 1807.
21. Madabathula, L. (2025). A governance-driven enterprise lakehouse architecture for real-time analytics and machine learning enablement. International Journal of Applied Mathematics, 38(12s), 5022–5033.
22. Umamaheswari, S., Harsha, D., Babu, T. S., Paramasivan, M., Bitragunta, S. L. V., & Padmasuresh, L. (2026, August). IoT-Based Smart Sensor Network for Adventure Park Safety and Management. In 2026 9th International Conference on Circuit, Power & Computing Technologies (ICCPCT) (pp. 1898-1902). IEEE.
23. Polamarasetty, V. K. (2025). Scalable Workday benefits integration frameworks for enterprise HR technology. International Journal of Computer Technology and Electronics Communication, 8(2), 10483–10489.
24. Selvarajan, K. (2025). AI-Driven Enterprise Supply Chain Intelligence: A Technical Deep Dive. Journal of Computer Science and Technology Studies, 7(2), 612-617.
25. Nelavala, M. M., Joseph, A., & Augustine, A. (2026). Protocol-aware chaos engineering for SWIFT Gpi-compatible microservices: A framework for five-nines cross-border payment resilience. Journal of Intelligent Decision Making and Information Science, 3(10s), 621–637.
26. Reddy, K. V. (2024). Accelerating Functional Coverage Closure Through Iterative Machine Learning. Int. J. Comput. Appl. Inf. Technol, 7, 1401-1411.
27. Pochincharla, S., & Devineni, A. (2023). Automated compliance-driven patch management and security hardening in multi-cloud banking infrastructure. International Journal of Advances in Signal and Image Sciences, 57–62.
28. Vani, M., & Dadlani, D. (2026, July). Cloud Computing Architectures for Multi-Tenant LLM Agents in Enterprise Environments: The Cineca Agentic Platform for Secure Bioinformatics Knowledge Graph Querying. In 2026 IEEE 9th International Conference on Big Data and Artificial Intelligence (BDAI) (pp. 175-180). IEEE.
29. Challa, A., & Konatham, M. R. (2024). Self-Healing CI/CD Pipelines with Feedback-Loop Automation: Building Fault-Tolerant CI/CD Systems Using Anomaly Detection and Automated Rollback Logic. Int. J. Intell. Syst. Appl. Eng, 12(23s), 3217.
30. Anumula, S. K. (2025). Design-based supply Chain operations research model: fostering resilience and sustainability in modern supply Chains. arXiv preprint arXiv:2511.01878.
31. Rekulapalli, K., Kagga, S. R., Ayyagari, V., Akula, A., & Raj Akula, R. (2026). AI in HRM: Enhancing Workforce Competency and Organizational Effectiveness. Available at SSRN 6762998.
32. Karrothu, A. (2025). Engineering scalable cloud-native distributed systems for real-time security telemetry ingestion and threat detection. Journal of Computational Analysis and Applications (JoCAAA), 34(12), 1175–1188. https://eudoxuspress.com/index.php/pub/article/view/5221
33. Ahuja, D. (2026, March). Performance Analysis of a Cloud-Native Web Application Deployed on Kubernetes. In 2026 14th International Symposium on Digital Forensics and Security (ISDFS) (pp. 01-06). IEEE.
34. Ivanov, T., Shrestha, G., Vemireddy, K., Pyayt, A., & Gubanov, M. (2026, May). Hemolix. extract. v: Llm-based information extraction for documents with ai-based plan selection. In Companion of the International Conference on Management of Data (pp. 54-57).
35. Elliott, S., & Roy, S. (2026, April). Critical Transit Infrastructure in Smart Cities and Urban Air Quality: A Multi-City Seasonal Comparison of Ridership and PM 2.5. In 2026 IEEE Conference on Technologies for Sustainability (SusTech) (pp. 1-8). IEEE.
36. Vaduguru, N. N. (2025). Automating the Capital General Rate Case Filing Process Using SAP HANA: A Digital Transformation Approach for Regulatory Compliance. The USA Journals TAJET, 7(06), 178-192.
37. Tarigoppula, S. (2023). Cloud-native Oracle database modernization using intelligent migration frameworks and automated recovery architectures. International Journal of Science, Research and Technology, 6(6), 11132–11144.
38. Gajjela, H., & Kari, M. (2024). Secure Multi-Tenant AI Architecture Enhances Enterprise AI Adoption Through Tenant Trust Using PLS-SEM in India’s Salesforce Cloud Industry. International Journal of Engineering Science & Humanities, 14(2), 253-271.
39. Sandhu, Y. S. (2025). Scalable pipeline orchestration through intelligent dependency-aware recovery and performance optimization. International Journal of Future Innovative Science and Technology (IJFIST), 8(5), 15712–15722.
40. Gudipuri, N. (2023). Causality-Preserving Distributed Decision Fabrics for AI-Native Financial Enterprise Architectures. The Eastasouth Management and Business, 1(03), 128-136.
